Does Vaping Regularly Cause “Leaky Gut Syndrome”?

Source from:  Vapingpost 01/13/2021

The study titled, “E-cigarettes compromise the gut barrier and trigger inflammation,” was led by Soumita Das, PhD, an associate professor of pathology, and Pradipta Ghosh, MD, professor of cellular and molecular medicine at UC San Diego School of Medicine and Moores Cancer Center, at UC San Diego School of Medicine.

By generating 3D models of human intestinal tracts from patient cells, and testing how vapour interacts with them in a lab environment, the research team concluded that chronic (not acute) exposure to nicotine-free e-cigarettes led to “Leaky Gut” Syndrome. The condition is know to contribute to a variety of diseases and conditions, including inflammatory bowel disease, dementia, certain cancers, atherosclerosis, liver fibrosis, diabetes and arthritis.

“The gut lining is an amazing entity. It is comprised of a single layer of cells that are meant to seal the body from the trillions of microbes, defend our immune system, and at the same time allow absorption of essential nutrients,” said Ghosh. “Anything we eat or drink, our lifestyle choices in other words, has the ability to impact our gut microbes, the gut barrier and overall health. Now we know that what we smoke, such as e-cigarettes, negatively impacts it as well.”

“Numerous chemicals are created when these two are heated to generate the fumes in vaping that cause the most damage, for which there are no current regulations,” said Ghosh. “The safety of e-cigarettes have been debated fiercely on both sides. Nicotine content, and its addictive nature, has always been the major focus of those who argue against its safety, whereas lack of chemicals in the carcinogens that are present in the cigarette smoke has been touted by the makers of e-cigarettes when marketing these products as a ‘healthy alternative.’ In reality, it’s the chemicals making up the vapor liquid that we should be more concerned about as they are the cause of gut inflammation.”